Cesium Carbonate (Cesium Carbon Oxide) (Cs2CO3)-Powder

Characteristic




Caesium carbonate or cesium carbonate is a white crystalline solid compound. Caesium carbonate has a high solubility in polar solvents such as water, alcohol and DMF.




Chemical formula：Cs2CO3

Molar mass：325.82 g/mol

Appearance：white powder

Density：4.072 g/cm3

Melting point：610 °C (1,130 °F; 883 K) (decomposes)

Solubility in water：2605 g/L (15 °C)

Solubility in ethanol：110 g/L

Solubility in dimethylformamide：119.6 g/L

Solubility in dimethyl sulfoxide：361.7 g/L

Solubility in sulfolane：394.2 g/L

Solubility in methylpyrrolidone：723.3 g/L

Magnetic susceptibility (χ)：-103.6·10−6 cm3/mol







Application




Many of the properties of cesium carbonate in organic synthesis are derived from the soft lewis acidity of cesium ions, which allows it to dissolve in organic solvents such as alcohols, DMF, and ether.Cesium carbonate also has important applications in the synthesis of natural products. For example, cesium carbonate can be used as an inorganic base in the synthesis of lipogrammistin-a compound in the key step of closed-loop reaction to obtain closed-loop products with high yield.In addition, cesium carbonate has important applications in solid supported organic reactions due to its good solubility in organic solvents.Cesium carbonate, as a base, can also esterify benzoic acid with solid supporting halide under microwave irradiation.